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BioMat05 - PSN

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Phase-based Self-assembling Nanomaterials

Molecular self-assembly with DNA is an attractive route for building nanodevices with user-defined functionalities. DNA-based objects featuring complex three-dimensional (3D) nanoscale shapes in which thousands of DNA basepairs (bp) are placed with subnanometer-precision at designed positions have been successfully fabricated. A key challenge for a DNA-based approach to nanotechnology is the production of desired objects at the gram scale at affordable prices to enable applications in areas ranging from chemistry to health. To meet this challenge here we propose a scientific engineering approach that combines biophysical assembly studies with process engineering to elucidate basic assembly principles and process limitations. The production of single-stranded DNA (ssDNA) molecules plays a key role for creating DNA-based nanodevices. The objectives of the engineering partner (DWB) include the selection and optimization of ssDNA production principles, the development of ssDNA production processes for large-scale preparation of ssDNA, and the reaction- engineering characterization of several production approaches to yield quantitative data for scale-up and economic evaluations. The objectives of the science partner (HD) comprise exploring the influence of DNA strand composition, sequences, and lengths on assembly processes, and determining reaction schemes that lead to time / reactant efficient production of high-quality objects. The project will focus on the scaled-up production of objects for use in other projects within the Focus Area Biomaterials.

01-01-1970
IGSSE setup of interdisciplinary research in project teams
16.05.17

Apply now: 12th call for proposals

IGSSE supports up to 10 new project teams

Call closes 2 July 2017

11.06.17

Apply now: IGSSE travel grant for ICCE 2017

28-29 September 2017, TU Darmstadt

Submission deadline for abstracts: 18 June 2017

08.06.17

IGSSE Forum 2017

29-31 May 2017, TUM Science and Study Center Raitenhaslach, Burghausen

14.05.17

Climate-KIC: Join the PhD Catapult

Two-week thematic summer schools across Europe

04.05.17

IAS Symposium: Selected topics in science and technology

8-10 May 2017, IAS Building, Garching Campus

02.05.17

IAS Coffee Talk with PTL Florian Praetorius

3 May 2017, 1 pm, TUM IAS Building, Garching Campus

23.02.16

10th IGSSE Forum

1 - 4 June 2016, TUM Science and Study Center, Burghausen

05.06.16

10th IGSSE Forum

Smart cooperation - science and technology in, with and for society

15.12.15

The Science of Cooking

Doctoral Candidates explore the Secrets of a great Dinner

26.11.15

ATUMS@IGSSE

Having heard of a great Canadian Kick-Off Meeting, everyone at IGSSE was thrilled to welcome the...

20.11.15

Breakfast at IGSSE´s

Meet the IGSSE team every other month! All the things IGSSE members wanted to asked but never dared...

13.10.15

Save the Date: Canadian ATUMS Speaker on "Global Science- Global Career"

26. November 2015, 6-8 pm, IAS Faculty Club, Garching Campus

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Friday, 09. June 2017
Workshop: Standing up for science
9 June 2017, 9am-4pm, Brussels
Apply now: McKinsey 'Forschergeist' symposium
9-11 June 2017, Berlin For doctoral researchers and postdocs!