Direkt zum Inhalt springen

6.02 Interdisciplinary Modeling of Biofilms

About

Nature tends to use the cheap and available materials at small length scales to build species, where viscoelasticity is a common practice. Biofilms, an abundant example of such species, are microbial communities consisting of microorganisms surrounded by an extracellular polymeric matrix (EPS). Biofilms are a preferred way of microbial existence as they provide protection against existing physical forces and chemical attack, if necessary. Formation of a biofilm is desirable in some cases (wastewater treatment, biochemical production), whereas in others it poses severe problems (marine equipment fouling, biomaterial-related infections). Biofilm architecture, mechanics and its interaction with surrounding fluid can have profound influence on their behavior and potential treatments, i.e. susceptibility to sloughing, and antibiotic resistance. Consequently, a better understanding of biofilms will require reliable experimental findings and detailed models that are capable of predicting biofilm architecture and growth, and their interaction with surrounding fluids.

In This work, we propose to design an experiment to measure the mechanical properties and characteristics of biofilms in situ in a novel microfluidic device by applying a finite load on the structure. In order to extract the viscoelastic material properties out of the experimental data, a modified version of the in‐house Finite Element Code will be used initially. Furthermore, The advanced viscoelastic material will be implemented in a state of the art Fluid-Structure Interaction (FSI) model to study the formation of complex biofilm structures, such as ripples and streamers. Though composed of microorganisms, a biofilm is a macro-scale structure that interacts with its environment as a macro-scale material. The findings in this proposed study will shed a light on the missing understanding of the macro-scale dynamic lives of bacterial aggregates living in complex interactive environments.

 

.

01-01-1970

 

12.07.17

EuroTech network event: From excellent research to excellent innovation – are universities ready for the future?

20 September 2017, 6-8pm, Representation of the Free State of Bavaria to the European Union,...

10.07.17

More fun than anyone: IGSSE@ TUM´s dragon boat race

Although the IGSSE team did not make it to Head of the Olympic Lake in 2017 - their fun was...

11.06.17

Apply now: IGSSE travel grant for ICCE 2017

28-29 September 2017, TU Darmstadt

Submission deadline for abstracts: 18 June 2017

23.02.16

10th IGSSE Forum

1 - 4 June 2016, TUM Science and Study Center, Burghausen

05.06.16

10th IGSSE Forum

Smart cooperation - science and technology in, with and for society

15.12.15

The Science of Cooking

Doctoral Candidates explore the Secrets of a great Dinner

26.11.15

ATUMS@IGSSE

Having heard of a great Canadian Kick-Off Meeting, everyone at IGSSE was thrilled to welcome the...

20.11.15

Breakfast at IGSSE´s

Meet the IGSSE team every other month! All the things IGSSE members wanted to asked but never dared...

13.10.15

Save the Date: Canadian ATUMS Speaker on "Global Science- Global Career"

26. November 2015, 6-8 pm, IAS Faculty Club, Garching Campus

20 < lib.tabbedcontent
July - 2017
Sun Mon Tue Wed Thu Fri Sat
  01
02 03 04 05 06 07 08
09
10
11
12
13 14 15
16
17
18
19
20 21 22
24 25
26
27 28 29
30 31  
Wednesday, 12. July 2017
Monday, 17. July 2017
Apply now: TUM-Imperial Global Fellows Summer School
17-21 July 2017, Burghausen, Germany
Wednesday, 19. July 2017
Wednesday, 26. July 2017
Register now: ICMSB 2017
26-28 July 2017, TUM Study and Science Center, Raitenhaslach