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6.02 Interdisciplinary Modeling of Biofilms

About

Nature tends to use the cheap and available materials at small length scales to build species, where viscoelasticity is a common practice. Biofilms, an abundant example of such species, are microbial communities consisting of microorganisms surrounded by an extracellular polymeric matrix (EPS). Biofilms are a preferred way of microbial existence as they provide protection against existing physical forces and chemical attack, if necessary. Formation of a biofilm is desirable in some cases (wastewater treatment, biochemical production), whereas in others it poses severe problems (marine equipment fouling, biomaterial-related infections). Biofilm architecture, mechanics and its interaction with surrounding fluid can have profound influence on their behavior and potential treatments, i.e. susceptibility to sloughing, and antibiotic resistance. Consequently, a better understanding of biofilms will require reliable experimental findings and detailed models that are capable of predicting biofilm architecture and growth, and their interaction with surrounding fluids.

In This work, we propose to design an experiment to measure the mechanical properties and characteristics of biofilms in situ in a novel microfluidic device by applying a finite load on the structure. In order to extract the viscoelastic material properties out of the experimental data, a modified version of the in‐house Finite Element Code will be used initially. Furthermore, The advanced viscoelastic material will be implemented in a state of the art Fluid-Structure Interaction (FSI) model to study the formation of complex biofilm structures, such as ripples and streamers. Though composed of microorganisms, a biofilm is a macro-scale structure that interacts with its environment as a macro-scale material. The findings in this proposed study will shed a light on the missing understanding of the macro-scale dynamic lives of bacterial aggregates living in complex interactive environments.

 

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01-01-1970
14.02.17

IGSSE Forum 2017

29-31 May 2017, TUM Science and Study Center Raitenhaslach, Burghausen

IGSSE setup of interdisciplinary research in project teams
16.05.17

Apply now: 12th call for proposals

IGSSE supports up to 10 new project teams

Call closes 2 July 2017

14.05.17

Climate-KIC: Join the PhD Catapult

Two-week thematic summer schools across Europe

04.05.17

IAS Symposium: Selected topics in science and technology

8-10 May 2017, IAS Building, Garching Campus

03.05.17

PhD position in project team INTERACT

Deadline for applications 15 June 2017

02.05.17

IAS Coffee Talk with PTL Florian Praetorius

3 May 2017, 1 pm, TUM IAS Building, Garching Campus

14.02.17

IGSSE Forum 2017

29-31 May 2017, TUM Science and Study Center Raitenhaslach, Burghausen

05.06.16

10th IGSSE Forum

Smart cooperation - science and technology in, with and for society

15.12.15

The Science of Cooking

Doctoral Candidates explore the Secrets of a great Dinner

26.11.15

ATUMS@IGSSE

Having heard of a great Canadian Kick-Off Meeting, everyone at IGSSE was thrilled to welcome the...

20.11.15

Breakfast at IGSSE´s

Meet the IGSSE team every other month! All the things IGSSE members wanted to asked but never dared...

13.10.15

Save the Date: Canadian ATUMS Speaker on "Global Science- Global Career"

26. November 2015, 6-8 pm, IAS Faculty Club, Garching Campus

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Tuesday, 02. May 2017
IAS Coffee Talk with PTL Florian Praetorius
3 May 2017, 1 pm, TUM IAS Building, Garching Campus
Thursday, 04. May 2017
IAS Symposium: Selected topics in science and technology
8-10 May 2017, IAS Building, Garching Campus
Wednesday, 10. May 2017
Project team ROLITOS in a German documentary
10 May 2017, 11.30 pm Suedwestrundfunk (TV) 30 May 2017, 10.30 pm Bayerischer Rundfunk (TV)
Sunday, 14. May 2017
Climate-KIC: Join the PhD Catapult
Two-week thematic summer schools across Europe
Monday, 15. May 2017
Apply now: 12th call for proposals
IGSSE supports up to 10 new project teams Call closes 2 July 2017
Wednesday, 17. May 2017
Podiumsdiskussion: Frauenförderung - Quo vadis?
17. Mai 2017, 14- 16 Uhr, Hochschule Weihenstephan-Triesdorf, Weidenbach
Friday, 19. May 2017
Tuesday, 23. May 2017
Monday, 29. May 2017
IGSSE Forum 2017
29-31 May 2017, TUM Science and Study Center Raitenhaslach, Burghausen