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26.01.17 15:42

Biomaterials Talk: Dissecting the roles of formins in cell cortex formation

27 January 2017, 1 pm, Room PH 127, Garching Campus

Jan Faix of the Medizinische Hochschule Hanover gives insights into his research. Read the abstract of his talk here:

Morphogenesis, the immune response or the spread of cancer all depend on the ability of cells to migrate. Cell migration is driven by the establishment of disparity between the cortical properties of the softer front and the more rigid rear to allowing front extension and actomyosin-based rear contraction but depends on cell type and environmental context. The contractile actin cortex is a thin layer of bundled or crosslinked actin filaments, non-muscle myosin II, and associated proteins beneath the plasma membrane of eukaryotic cells. Assembly and contraction of this layer generates cortical tension and plays a central role in migration, cell division, and tissue morphogenesis. Despite its significance, the assembly, structural organization, membrane attachment and mechanics of the actin-rich cortex are still not well understood. Using a combination of imaging, molecular biology and biophysics we have identified a number of formins as key regulators and seek to understand the functions of these proteins cell cortex function, the underlying pathways and principles that underlie migration trough complex environments.

For more information, please contact Andreas Bausch abausch(at)ph.tum.de.

01-01-1970
IGSSE setup of interdisciplinary research in project teams
16.05.17

Apply now: 12th call for proposals

IGSSE supports up to 10 new project teams

Call closes 2 July 2017

11.06.17

Apply now: IGSSE travel grant for ICCE 2017

28-29 September 2017, TU Darmstadt

Submission deadline for abstracts: 18 June 2017

08.06.17

IGSSE Forum 2017

29-31 May 2017, TUM Science and Study Center Raitenhaslach, Burghausen

14.05.17

Climate-KIC: Join the PhD Catapult

Two-week thematic summer schools across Europe

04.05.17

IAS Symposium: Selected topics in science and technology

8-10 May 2017, IAS Building, Garching Campus

02.05.17

IAS Coffee Talk with PTL Florian Praetorius

3 May 2017, 1 pm, TUM IAS Building, Garching Campus

23.02.16

10th IGSSE Forum

1 - 4 June 2016, TUM Science and Study Center, Burghausen

05.06.16

10th IGSSE Forum

Smart cooperation - science and technology in, with and for society

15.12.15

The Science of Cooking

Doctoral Candidates explore the Secrets of a great Dinner

26.11.15

ATUMS@IGSSE

Having heard of a great Canadian Kick-Off Meeting, everyone at IGSSE was thrilled to welcome the...

20.11.15

Breakfast at IGSSE´s

Meet the IGSSE team every other month! All the things IGSSE members wanted to asked but never dared...

13.10.15

Save the Date: Canadian ATUMS Speaker on "Global Science- Global Career"

26. November 2015, 6-8 pm, IAS Faculty Club, Garching Campus

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Friday, 09. June 2017
Workshop: Standing up for science
9 June 2017, 9am-4pm, Brussels
Apply now: McKinsey 'Forschergeist' symposium
9-11 June 2017, Berlin For doctoral researchers and postdocs!